Research
Science and Technology that enable the analysis of patients’ minute biopsy samples in the native states to reveal the fundamental causes of diseases and yield intervention points for treatment are in critical demand. Research in Wang group leverages interdisciplinary approaches that merge material science, biochemistry, bioengineering and nanotechnology to address such multifaceted challenges. Students receive training in biochemistry, biophysics, bioanalytical chemistry, surface chemistry, composite materials and cell biology through research projects, such as: a) developing high-performance biocomposite materials with tunable biochemical composition and biophysical properties, and stimuli-responsive for tissue repair and cell therapeutics; b) creating a salivary sensor device, coupled with optical spectroscopy and imaging, machine learning and nano/microfabrication, to assess the risk of periodontitis and comorbidities; c) generating silk based fibers to mimick the aligned fibrous collagen in extracellular matrix for innovative biomedical and industrial devices; and d) designing and synthesizing photothermo-responsive polymer as gating material for aroma compound and drug molecule encapsulation and controllable release.
Dr. Wang’s research are currently funded by National Institute of Health and National Science Foundation. She is a Standing Member of NIH Cellular and Molecular Technologies (CMT) Study Section, an Associate Editor of Frontiers in Bioengineering and Biotechnology, and is on the Editorial Boards of Bioengineering and Journal of Functional Biomaterials.
Research
Science and Technology that enable the analysis of patients’ minute biopsy samples in the native states to reveal the fundamental causes of diseases and yield intervention points for treatment are in critical demand. Research in Wang group leverages interdisciplinary approaches that merge material science, biochemistry, bioengineering and nanotechnology to address such multifaceted challenges. Students receive training in biochemistry, biophysics, bioanalytical chemistry, surface chemistry, composite materials and cell biology through research projects, such as: a) developing high-performance biocomposite materials with tunable biochemical composition and biophysical properties, and stimuli-responsive for tissue repair and cell therapeutics; b) creating a salivary sensor device, coupled with optical spectroscopy and imaging, machine learning and nano/microfabrication, to assess the risk of periodontitis and comorbidities; c) generating silk based fibers to mimick the aligned fibrous collagen in extracellular matrix for innovative biomedical and industrial devices; and d) designing and synthesizing photothermo-responsive polymer as gating material for aroma compound and drug molecule encapsulation and controllable release.
Dr. Wang’s research are currently funded by National Institute of Health and National Science Foundation. She is a Standing Member of NIH Cellular and Molecular Technologies (CMT) Study Section, an Associate Editor of Frontiers in Bioengineering and Biotechnology, and is on the Editorial Boards of Bioengineering and Journal of Functional Biomaterials.
Scholarly Work
“A Review on Saliva Based Health Diagnostics: Biomarker Selection and Future Directions”, Kumari S, Samara M, Ampadi Ramachandran R, Gosh S, George H, Wang R, Pesavento RP, Mathew MT. A Review on Saliva-Based Health Diagnostics: Biomarker Selection and Future Directions. Biomed Mater Devices. (2023) Jun 6:1-18. doi:10.1007/s44174-023-00090-z.
“Machine learning enabled multiplex detection of periodontal pathogens by surface-enhanced Raman spectroscopy” Rathnayake R.A.C., Zhao Z., McLaughlin N., Chen L., Yan Y., Xie Q., Li W., Mathew M., Wang R.R. Int. J. Biol. Macromol. (2024), 257(2):128773. doi: 10.1016/j.ijbiomac.2023.128773.
“Electrospun Silk-ICG Composite Fibers and the Application towards Hemorrhage Control”, Ayesha Siddiqua, Elwin Clutter, Olga Garklavs, Hemalatha Kanniyappan, Rong R. Wang, J. Functional Biomaterials. J. Funct. Biomater. (2024), 15, 272. https://doi.org/ 10.3390/jfb15090272.