BS Chemical Engineering University of Massachusetts – Amherst 2006
PhD Chemical and Biomolecular Engineering Engineering, Johns Hopkins University, 2012
Postdoc Biomedical Engineering Tufts University 2012-2016
The overall objectives of my research are to develop clinically translatable tissue regeneration and drug delivery strategies, and three-dimensional, in vitro human disease models using biologically-derived biomaterials. We will utilize techniques from engineering, chemistry and biology to address these research areas, including chemical modifications to alter drug-material interactions, small molecule and macromolecule conjugates to direct cell fate, and multi-cellular tissue/disease systems for paracrine signaling and direct cell-cell interactions. My research is focused on biomaterials and their applications in tissue engineering and drug delivery. During my PhD, I worked with photo-crosslinked PEGDA hydrogel systems to study repair strategies for articular cartilage diseases. I also developed low density, bioactive-electrospun fiber scaffolds for repair of articular cartilage defects. My postdoctoral research used silk fibroin proteins from Bombyx mori silkworm cocoons for (1) drug delivery systems for oncology therapeutics and HIV treatment/prevention and (2) tissue regeneration of the kidney and pancreas. In the lab and the classroom, I truly enjoy teaching. I am especially excited to mentor students on their Major Qualifying Projects. I strive to ensure that students are able to (1) apply theoretical concepts to practical applications and (2) fully understand the tasks being performed.
BS Chemical Engineering University of Massachusetts – Amherst 2006
PhD Chemical and Biomolecular Engineering Engineering, Johns Hopkins University, 2012
Postdoc Biomedical Engineering Tufts University 2012-2016
The overall objectives of my research are to develop clinically translatable tissue regeneration and drug delivery strategies, and three-dimensional, in vitro human disease models using biologically-derived biomaterials. We will utilize techniques from engineering, chemistry and biology to address these research areas, including chemical modifications to alter drug-material interactions, small molecule and macromolecule conjugates to direct cell fate, and multi-cellular tissue/disease systems for paracrine signaling and direct cell-cell interactions. My research is focused on biomaterials and their applications in tissue engineering and drug delivery. During my PhD, I worked with photo-crosslinked PEGDA hydrogel systems to study repair strategies for articular cartilage diseases. I also developed low density, bioactive-electrospun fiber scaffolds for repair of articular cartilage defects. My postdoctoral research used silk fibroin proteins from Bombyx mori silkworm cocoons for (1) drug delivery systems for oncology therapeutics and HIV treatment/prevention and (2) tissue regeneration of the kidney and pancreas. In the lab and the classroom, I truly enjoy teaching. I am especially excited to mentor students on their Major Qualifying Projects. I strive to ensure that students are able to (1) apply theoretical concepts to practical applications and (2) fully understand the tasks being performed.
Harris JC, Coburn JM, Kajdacsy-Balla A, Kaplan DL, Chiu B. (2016) Sustained delivery of vincristine inside an orthotopic mouse sarcoma model decreases tumor growth. Journal of Pediatric Surgery. 51(12):2058-62.
Applegate MB, Partlow BP, Coburn J, Marelli B, Pirie C, Pineda R, Kaplan DL, Omenetto FG. (2016) Photocrosslinking of silk fibroin using riboflavin for ocular prostheses. Advanced Materials, 8(12):2417-20.
Kim C, Jeon OH, Kim do H, Chae JJ, Shores L, Bernstein N, Bhattacharya R, Coburn JM, Yarema KJ, Elisseeff JH. (2016) Local delivery of a carbohydrate analog for reducing arthritic inflammation and rebuilding cartilage. Biomaterials, 83:93-101.
Seib FP, Coburn J, Konrad I, Klebanov N, Jones GT, Blackwood B, Charest A, Kaplan DL, Chiu B. (2015) Focal therapy of neuroblastoma using silk films to deliver kinase and chemotherapeutic agents in vivo. Acta Biomaterialia, 20:32-8.
Bhattacharjee M, Coburn J, Centola M, Murab S, Barbero A, Kaplan DL, Martin I, Ghosh S. (2015) Tissue engineering strategies to study cartilage development, degeneration and regeneration. Advanced Drug Delivery Reviews, 84:107-22.
Spectrum News 1 spoke with Jeannine Coburn, assistant professor in the Department of Biomedical Engineering, about her $600,000 National Science Foundation CAREER Award to develop a transparent wound dressing that traces its origins to her homemade kombucha. Spectrum 1’s Louisville, Ky., outlet also featured Coburn’s research.
