SDG 3: Good Health & Well-Being - Ensure healthy lives and promote well-being for all at all ages
The ability of our biological tissues to adapt to their mechanical environment, and the ways in which our tissues are well suited for their own mechanical role within the body, is a constant source of wonder to me. I am interested in understanding the mechanical signals that are experienced within the skeleton during different types of physical activity, understanding what features of these signals stimulate bone to adapt its structure, and in developing noninvasive methods to quantify bone strength. One ongoing project examines biomechanical risk factors for bone stress injury in runners. We use high resolution quantitative computed tomography (CT) to image bone microstructure, and use these images to create computational models that simulate bone mechanical behavior. Another project uses a combination of clinical CT images, mechanical cadaver testing, and computational modeling to measure changes in bone strength in individuals with spinal cord injury who are participating in a clinical trial that targets bone health.
When teaching, I especially enjoy working with groups of students on both physical and computational experiments that explore this link between whole body biomechanics and the physiologic response of our musculoskeletal system. Biomechanics is incredibly relevant to every person’s life, since it dictates how and why we are able to perform certain physical tasks, why we become injured, and how we recover from an injury. In the classroom I try to connect more theoretical concepts to everyday experiences of my students, myself, and my family. At the graduate level, I mentor master’s and doctoral students and enjoy helping them develop into scientists who can ask good questions, communicate clearly, and carry out excellent technical experiments.
Visit Digital WPI to view student projects and research advised by Professor Troy
The ability of our biological tissues to adapt to their mechanical environment, and the ways in which our tissues are well suited for their own mechanical role within the body, is a constant source of wonder to me. I am interested in understanding the mechanical signals that are experienced within the skeleton during different types of physical activity, understanding what features of these signals stimulate bone to adapt its structure, and in developing noninvasive methods to quantify bone strength. One ongoing project examines biomechanical risk factors for bone stress injury in runners. We use high resolution quantitative computed tomography (CT) to image bone microstructure, and use these images to create computational models that simulate bone mechanical behavior. Another project uses a combination of clinical CT images, mechanical cadaver testing, and computational modeling to measure changes in bone strength in individuals with spinal cord injury who are participating in a clinical trial that targets bone health.
When teaching, I especially enjoy working with groups of students on both physical and computational experiments that explore this link between whole body biomechanics and the physiologic response of our musculoskeletal system. Biomechanics is incredibly relevant to every person’s life, since it dictates how and why we are able to perform certain physical tasks, why we become injured, and how we recover from an injury. In the classroom I try to connect more theoretical concepts to everyday experiences of my students, myself, and my family. At the graduate level, I mentor master’s and doctoral students and enjoy helping them develop into scientists who can ask good questions, communicate clearly, and carry out excellent technical experiments.
Visit Digital WPI to view student projects and research advised by Professor Troy
Scholarly Work
Professor Troy’s work focuses on understanding how forces applied to the musculoskeletal system can influence bone and joint health, function, and injury in adult men and women in health and disease, using a combination of computational modeling, medical image analysis, cadaver mechanical testing, and living human subjects in a clinical research setting.
- Full list of publications in PubMed
- Full list of publications on Google Scholar
- Full list of publications in Scopus
FEATURED WORKS:
Troy, K. L., Davis, I. S., & Tenforde, A. S. (2021). A narrative review of metatarsal bone stress injury in athletic populations: etiology, biomechanics, and management. PM&R, 13(11), 1281-1290.
Troy, K. L., Mancuso, M. E., Johnson, J. E., Wu, Z., Schnitzer, T. J., & Butler, T. A. (2020). Bone Adaptation in Adult Women Is Related to Loading Dose: A 12‐Month Randomized Controlled Trial. Journal of Bone and Mineral Research, 35(7), 1300-1312.
Mancuso, M. E., & Troy, K. L. (2020). Relating bone strain to local changes in radius microstructure following 12 months of axial forearm loading in women. Journal of Biomechanical Engineering, 142(11).
Morse, L. R., Biering-Soerensen, F., Carbone, L. D., Cervinka, T., Cirnigliaro, C. M., Johnston, T. E., ... & Craven, B. C. (2019). Bone mineral density testing in spinal cord injury: 2019 ISCD official position. Journal of Clinical Densitometry, 22(4), 554-566.
Johnson, J. E., & Troy, K. L. (2018). Simplified boundary conditions alter cortical-trabecular load sharing at the distal radius; A multiscale finite element analysis. Journal of Biomechanics, 66, 180-185.
PATENT:
“Systems and Methods for Early Detection of Fracture Healing”, PCT International Patent Application No. PCT/US2018/028251 Based in U.S. Provisional Patent Application No.: 62/487,190, filed: April 19, 2018 (issued)