BS Chemical Engineering University of Massachusetts – Amherst 2006
PhD Chemical and Biomolecular Engineering Engineering, Johns Hopkins University, 2012
Postdoc Biomedical Engineering Tufts University 2012-2016
The overall objectives of my research are to develop clinically translatable tissue regeneration and drug delivery strategies, and three-dimensional, in vitro human disease models using biologically-derived biomaterials. We will utilize techniques from engineering, chemistry and biology to address these research areas, including chemical modifications to alter drug-material interactions, small molecule and macromolecule conjugates to direct cell fate, and multi-cellular tissue/disease systems for paracrine signaling and direct cell-cell interactions. My research is focused on biomaterials and their applications in tissue engineering and drug delivery. During my PhD, I worked with photo-crosslinked PEGDA hydrogel systems to study repair strategies for articular cartilage diseases. I also developed low density, bioactive-electrospun fiber scaffolds for repair of articular cartilage defects. My postdoctoral research used silk fibroin proteins from Bombyx mori silkworm cocoons for (1) drug delivery systems for oncology therapeutics and HIV treatment/prevention and (2) tissue regeneration of the kidney and pancreas. In the lab and the classroom, I truly enjoy teaching. I am especially excited to mentor students on their Major Qualifying Projects. I strive to ensure that students are able to (1) apply theoretical concepts to practical applications and (2) fully understand the tasks being performed.
BS Chemical Engineering University of Massachusetts – Amherst 2006
PhD Chemical and Biomolecular Engineering Engineering, Johns Hopkins University, 2012
Postdoc Biomedical Engineering Tufts University 2012-2016
The overall objectives of my research are to develop clinically translatable tissue regeneration and drug delivery strategies, and three-dimensional, in vitro human disease models using biologically-derived biomaterials. We will utilize techniques from engineering, chemistry and biology to address these research areas, including chemical modifications to alter drug-material interactions, small molecule and macromolecule conjugates to direct cell fate, and multi-cellular tissue/disease systems for paracrine signaling and direct cell-cell interactions. My research is focused on biomaterials and their applications in tissue engineering and drug delivery. During my PhD, I worked with photo-crosslinked PEGDA hydrogel systems to study repair strategies for articular cartilage diseases. I also developed low density, bioactive-electrospun fiber scaffolds for repair of articular cartilage defects. My postdoctoral research used silk fibroin proteins from Bombyx mori silkworm cocoons for (1) drug delivery systems for oncology therapeutics and HIV treatment/prevention and (2) tissue regeneration of the kidney and pancreas. In the lab and the classroom, I truly enjoy teaching. I am especially excited to mentor students on their Major Qualifying Projects. I strive to ensure that students are able to (1) apply theoretical concepts to practical applications and (2) fully understand the tasks being performed.
Ornell KJ, Chiu, B, Coburn JM. (2020) Development of a dinutuximab delivery system using silk foams for GD2 targeted neuroblastoma cell death. Journal of Biomedical Research Part A. 109(8):1393-1405. 2020
van ZyL E, Coburn JM. (2019) Hierarchical structure of bacterial-derived cellulose and impact on biomedical applications. Current Opinion in Chemical Engineering, 24:122-130. 2019
Villarreal-Otalvaro C, Coburn JM. (2021) Fabrication methods and form factors of gellan gum-based materials for drug delivery and anti-cancer applications. Accepted ACS Biomaterials Science and Engineering. DOI: 10.1021/acsbiomaterials.1c00685 2021
Ornell KJ, Coburn JM. (2019) Developing preclinical models of neuroblastoma: driving therapeutic testing. BMC Biomedical Engineering, 1:33. 2019
Carnes ME, Gonyea CR, Mooney RG, Njihia JW, Coburn JM, Pins GD. (2020) Horseradish peroxidase-catalyzed crosslinking of fibrin microthread scaffolds. Tissue Engineer Part C. 26(6):317-331. 2020
Ornell KJ, Phan NV, Lozada D, Coburn JM. (2019) Controlling methacryloyl substitution of chondroitin sulfate: Injectable hydrogels with tunable long-term drug release profiles. Journal of Materials Chemistry B. 7:2151-2161. 2019
Spectrum News 1 spoke with Jeannine Coburn, assistant professor in the Department of Biomedical Engineering, about her $600,000 National Science Foundation CAREER Award to develop a transparent wound dressing that traces its origins to her homemade kombucha. Spectrum 1’s Louisville, Ky., outlet also featured Coburn’s research.
